Berbamine相关论文
Alcoholic liver disease (ALD) has become one of the leading causes of death in the world.Berbamine (BM),a natural produc......
Myocardial infarction resulting from coronary atherosclerosis is the leading cause of death in modern society.Reperfusio......
,Berbamine, a novel nuclear factor κB inhibitor, inhibits growth and induces apoptosis in human myel
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Aim: The aim of this study was to explore the effects and mechanism of berbamine on imatinib-resistant BCR-ABL-positive ......
Ovarian cancer is a common and lethal cancer affecting women globally.Berbamine is a natural compound from the plant Ber......
Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-med
Background Currently, resistance and relapse are still major problems in acute promyelocytic leukemia (APL) cases.Thus, ......
Sankezhen (Berberidis Radix) is a traditional Chinese materia medica,cold in nature and bitter in taste,for treating syn......
Berbamine induces apoptosis in human hepatoma cell line SMMC7721 by loss in mitochondrial transmembr
Objective: To investigate the effect of berbamine on human hepatoma cell line SMMC7721. Methods: The effects of 24 h and......
Berbamine selectively induces apoptosis of human acute promyelocytic leukemia cells via survivin-med
Background Currently, resistance and relapse are still major problems in acute promyelocytic leukemia (APL) cases.Thus, ......
应用改变检测波长反相高效液相色谱法测定了5种小檗属植物根中的尖刺碱、小檗胺、异汉防已碱、非洲防己胺、药根碱、巴马亭和小檗碱......
目的阐明苦参碱和小檗胺抗心律失常作用弱于胺碘酮和RP58866的分子机制.方法采用冠脉结扎、电刺激和乌头碱诱导的心律失常模型观察......
本文用常规微电捉技术研究了小檗胺对人离体心房梳状肌自发性节律的影响。小檗胺可降低人心房梳状肌的自发性节律和4相除极斜率。......
本文叙述了肌球蛋白(MLC)及其激酶(MLCK)与磷酸二酯酶(PDE)的制备。以已知的CaM拮抗剂三氟啦嗪(TFP)为对照,检测了小檗胺(E_0)及其......
采用Langendorff离体大鼠心脏灌流模型,研究了小檗胺(BA)对心肌缺血—再灌注损伤的保护作用。离体心脏全心缺血40min后再灌注时,心......
本文采用小鼠体内扩散盒及脾结节法,结合骨髓有核细胞计数,探讨了小蘖胺对小鼠骨髓白细胞系造血功能的影响.该药能显著提高小鼠骨......
实验观察了盐酸小壁胺对射损伤小鼠免疫系统夜用并对体内脂质过氧化反应进行检测。结果显示:电镜观察预防用药照射组小鼠胸腺,脾淋巴......
目的:探讨小檗胺(BBM)对K562细胞增殖及凋亡的影响及其可能机制。方法:K562细胞分为5组,前4组为实验组,分别加入终浓度为0.8、8.0、40.......
本文研究了小檗胺对小鼠由绵羊红细胞,二硝基氯苯及同种异型脾细胞所诱导的迟发型超敏反应的影响。实验结果显示小檗胺能明显抑制小......
本文研究了小檗胺的抗炎活性,结果表明小檗胺在25mg.kg^-1.7d和50mg.kg^-1.7d剂量下对由角叉菜胶诱导的大鼠足趾肿胀及高岭土诱导的......
比较了2种结构相近的双苄基异喹啉生物碱粉防己碱、小檗胺与维拉帕米逆转多药抗药性的作用。结果,TTD,BBM和VRP在多药抗药的MCF-7/Adr和KBv200细胞对ADR和VCR均有明显......
本实验研究了小檗胺(Ber)对5-羟色胺(5-HT)引起的离体猪大脑基底动脉收缩反应的影响,并与对脑血管敏感的钙拮抗剂尼莫地平(Nimo)做......
本实验证明了无论是单用小檗胺,黑豆果油或两者合用均能预防大鼠血中胆固醇,甘油三酯,低密度脂蛋白含量的升高,复方用药不能增强其降血......
采用大鼠肾动脉夹闭方法制备肾缺血再灌注损伤模型,缺血60min后再灌注30min,肾皮质丙二醛含量及钙含量较缺血组增高,过氧化氢酶活性低于缺血组。......
研究小檗胺(Ber)对氯化钾(KCl)和哇巴因(Oua)诱导的家兔血管平滑肌细胞(VSMC)内游离钙(「Ca^2」i)的影响。培养的VSMC以荣光探针Flou-3/AM负载,通过激光共聚集显微镜检查法检测......
应用升白安治疗白细胞减少患者26例,并与利血生治疗25例对照,结果发现两者疗效近似,升白安作用见效快,且对某些顽固性的白细胞减少患者......
目的研究小檗胺诱导人白血病K562/Adr细胞凋亡及逆转多药耐药的作用及机理.方法采用MTT法测IC-50 值,流式细胞仪Annexin V FITC-PI......
Myocardial infarction resulting from coronary atherosclerosis is the leading cause of death in modern soci- ety. Reperfu......
为了探讨钙调素拮抗剂小檗胺(berbamine,BBM)逆转多药耐药的可能性及其机制,采用人红白血病细胞K562及其阿霉素(ADR)诱导的耐药细......
用MTT法测定了几种小檗胺类化合物对三种贴壁生长细胞生长增殖的影响。结果显示:MTT分析法比传统的活细胞计数法,单细胞克隆尖及^3H-TdR掺入法测定......
目的为了探讨小檗胺(berbamine,BBM)在体外及体内抗人前列腺癌细胞株细胞的作用及其可能的机制。方法选取前列腺癌LNCAP、PC3及CWR......
本文研究了不同结构的新型钙调查蛋白(CaM)拮抗剂--小檗胺(B0)及三种衍生物EBB、B4、B2)对宫颈癌细胞的生长曲线、单细胞克隆、^3H-TdR掺入、线粒全脱氢酶活性......